SynInnova Laboratories Inc.

SL-4987

Ambrisentan-d₃ (methoxy-d₃), >98% (HPLC)

Isotopic Purity :

99 atom % D

CAS No. :

[1046116-26-0]

Synonyms : (S)-2-((4,6-Dimethylpyrimidin-2-yl)oxy)-3-(methoxy-d₃)-3,3-diphenylpropanoic acid; BSF 208075-d₃; LU 208075-d₃

Price and Availability
Pack Size	Price in USD	Quantity	Availability	Shipping Status
5MG	680.00	- +	Back Order	Estimated to Ship on 01.20.2025
10MG	1280.00	- +	Back Order	Estimated to Ship on 01.20.2025

Chemical Properties
Mol. Formula : C₂₂H₁₉D₃N₂O₄	Mol. Weight : 381.45
Appearance : White to Off-white solid	Melting Point : Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Ambrisentan-d3 is a deuterium labelled version of Ambrisentan, which is a highly selective antagonist of the endothelin-1 type A receptor (ETAR), used in the treatment of pulmonary arterial hypertension (PAH).

References : Weiss J. et al.: Eur J Pharmacol, 660(2-3), 298-304, 2011; Yokoyama Y. et al.: Biol Pharm Bull, 37(3), 461-465, 2014; Weiss J. et al.: Biochem Pharmacol, 85(2), 265-273, 2013; Osano A. et al.: J. Pharmacol Sci, 124(1), 86-91, 2014; Buckley M. S. et al.: Expert Opin Drug Metab Toxicol, 7(3), 371-380, 2011.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SL-4987

Product Name : Ambrisentan-d₃ (methoxy-d₃)

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SL-4987

Ambrisentan-d3 (methoxy-d3), >98% (HPLC)

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