SynInnova Laboratories Inc.

SL-4987

Ambrisentan-d₃ (methoxy-d₃), >98% (HPLC)

Isotopic Purity :

99 atom % D

CAS No. :

[1046116-26-0]

Synonyms : (S)-2-((4,6-Dimethylpyrimidin-2-yl)oxy)-3-(methoxy-d₃)-3,3-diphenylpropanoic acid; BSF 208075-d₃; LU 208075-d₃

Price and Availability
Pack Size	Price in USD	Quantity	Availability	Shipping Status
5MG	680.00	- +	Back Order	Estimated to Ship on 12.15.2024
10MG	1280.00	- +	Back Order	Estimated to Ship on 12.15.2024

Chemical Properties
Mol. Formula : C₂₂H₁₉D₃N₂O₄	Mol. Weight : 381.45
Appearance : White to Off-white solid	Melting Point : Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Ambrisentan-d3 is a deuterium labelled version of Ambrisentan, which is a highly selective antagonist of the endothelin-1 type A receptor (ETAR), used in the treatment of pulmonary arterial hypertension (PAH).

References : Weiss J. et al.: Eur J Pharmacol, 660(2-3), 298-304, 2011; Yokoyama Y. et al.: Biol Pharm Bull, 37(3), 461-465, 2014; Weiss J. et al.: Biochem Pharmacol, 85(2), 265-273, 2013; Osano A. et al.: J. Pharmacol Sci, 124(1), 86-91, 2014; Buckley M. S. et al.: Expert Opin Drug Metab Toxicol, 7(3), 371-380, 2011.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SL-4987

Product Name : Ambrisentan-d₃ (methoxy-d₃)

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Related Products

SL-5000	rac-Ambrisentan methyl ester
SL-4990	(R)-Ambrisentan-d₃
SL-4991	(S)-4-Hydroxymethyl ambrisentan
SL-4992	(S)-4-Hydroxymethyl ambrisentan-d₃
SL-4999	Ambrisentan methyl ester
SL-2023	rac-Ambrisentan-d₃
SL-4989	(R)-Ambrisentan
SL-5003	Ethyl 2-hydroxy-3-methoxy-3,3-diphenylpropionate
SL-2472	4-Hydroxymethyl ambrisentan acyl glucuronide
SL-4997	Ambrisentan ethyl ester
SL-5004	Ethyl (S)-2-hydroxy-3-methoxy-3,3-diphenylpropionate
SL-5006	Methyl 2-hydroxy-3-methoxy-3,3-diphenylpropionate

SL-4987	Ambrisentan-d₃ (methoxy-d₃)
SL-4992	(S)-4-Hydroxymethyl ambrisentan-d₃
SL-4988	Ambrisentan-d₁₀ (diphenyl-d₁₀)
SL-4990	(R)-Ambrisentan-d₃
SL-5004	Ethyl (S)-2-hydroxy-3-methoxy-3,3-diphenylpropionate
SL-5738	Megestrol acetate EP impurity G
SL-5729	Megestrol-d₅ acetate
SL-5735	Megestrol acetate EP impurity D
SL-4993	(S)-4-Hydroxymethyl ambrisentan-d₁₀
SL-4276	Hydroxydehydro-nifedipine-carboxylate
SI-3233	N-(4-Fluorobenzyl)-1-methylpiperidin-4-amine
SL-5739	Megestrol acetate EP impurity H

SL-4987

Ambrisentan-d3 (methoxy-d3), >98% (HPLC)

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