[68693-11-8]    

Synonyms : 2-[(Diphenylmethyl)sulfinyl]acetamide; 2-(Benzhydrylsulfinyl)acetamide; rac-Modafinil

Applications : Modafinil displays neuroprotective and antiparkinsonian activity in a primate model of Parkinson's disease. Promotes vigilence and wakefulness without the central and peripheral side effects associated with conventional dopaminergic psychostimulants. Mechanism of action is not fully understood, possibly via modulation of catecholamine/GABAergic neurotransmission.

References : Ferraro L et al: Biol Psychiatry 42(12), 1181-1183, 1997; Jenner P et al: ExpBrain Res 133(2), 178-188, 2000; Madras B K et al: J PharmacolExp Ther 319(2), 561-569, 2006

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.