[221287-83-8] of the unlabelled compound

Synonyms : 2-[[(5-Nitro-2-thiazolyl)amino]carbonyl]phenyl β-D-glucopyranosiduronic acid-d₄ sodium salt; Tizoxanide-d₄ glucuronide sodium salt

Applications : This is a deuterium labelled glucuronide metabolite of Tizoxanide, It is a thiazolide anti-infective, is an active against anaerobic bacteria, protozoa, and a range of viruses in cell culture models, and is currently in phase II clinical development for treating chronic hepatitis C. Also, this is a COVID-19 related research chemical.

References : Theodos C. M. et al.: Antimicrob Agents Chemother, 42(8), 1959-1965, 1998; Fox L. M. et al.: Clin Infect Dis, 40(8), 1173-1180, 2005; Adagu I. S. et al.: J. Antimicrob Chemother, 49(1), 103-111, 2002; Korba B. E. et al. Antiviral Res, 77(1), 56-63, 2008; Cedillo-Rivera R. et al.: J. Eukaryot Microbiol, 49(3), 201-208, 2002.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.