SynInnova Laboratories Inc.

SL-6282

3-(3-Iodopropyl)-7,8-dimethoxy-1,3-dihydro-2H-benzo[d]azepin-2-one, >98%

CAS No. :

[148870-57-9]

MDL No. :

MFCD09955403

Price and Availability
Pack Size	Price in USD	Quantity	Availability	Shipping Status
1G	80.00	- +	Back Order	Estimated to Ship on 12.08.2024
5G	280.00	- +	Back Order	Estimated to Ship on 12.08.2024

Chemical Properties
Mol. Formula : C₁₅H₁₈INO₃	Mol. Weight : 387.22
Appearance : Solid	Melting Point : Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an advanced key intermediate in the preparation of Ivabradine related analogs, which is an orally bioavailable, hyperpolarization-activated, cyclic nucleotide-gated (HCN) channel blocker, used for the symptomatic management of stable heart-related chest pain and heart failure not fully managed by beta blockers.

References : Thollon C. et al.: Br. J. Pharmacol.,112(1), 37-42, 1994; Fang Y. et al.: J. Cardiovasc Pharmacol., 59(3), 260-7, 2012; Kroller-Schon S. et al.: Basic Res Cardiol.,106(6), 1147-58, 2011.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SL-6282

Product Name : 3-(3-Iodopropyl)-7,8-dimethoxy-1,3-dihydro-2H-benzo[d]azepin-2-one

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