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SL-6482

3-(Difluoromethoxy)-4-hydroxybenzoic acid, >98%


Price and Availability
Pack Size Price in USD Quantity Availability Shipping Status
50MG150.00 Back Order Estimated to Ship on 01.19.2025
500MG1280.00 Back Order Estimated to Ship on 01.19.2025
Chemical Properties
C8H6F2O4 204.13
White to Off-white solid Not available
For Laboratory research use only, not for drug, household or other uses.
Applications : This is an advanced key intermediate in the preparation of Roflumilast related analogs, which is a selective PDE4 inhibitor, used in the treatment of severe chronic obstructive pulmonary disease (COPD).
References : Hatzelmann A. et al.: Pulm Pharmacol Ther., 23 (4), 235-256, 2010; Rabe K. F. Br. J. Pharmacol., 163 (1), 53-67, 2011; Hatzelmann A. et al.: J. Pharmacol Exp Ther., 297 (1), 267-279, 2001; Richmond B. W. et al.: Nat. Commun. 7, 11240, 2016.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SL-6482

Product Name : 3-(Difluoromethoxy)-4-hydroxybenzoic acid

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