MFCD30146111

[19916-73-5] of the unlabelled compound

Synonyms : 2-Amino-6-(phenyl-d₅-methoxy)-9H-purine

Applications : It is a deuterium labelled analogue of O(6)-benzylguanine, is an antineoplastic agent which binds the DNA repair enzyme O(6)-alkylguanine DNA alkyltransferase (AGT), resulting in inhibition of AGT-mediated DNA repair. It is widely used in various DNA repair mechanism studies and can be used as clinical reference standard.

References : Dolan. M. E. et. al.: Clin. Cancer Res., 06, 01, 1997.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.