SynInnova Laboratories Inc.

SL-678

O6-(3-fluorobenzyl)guanine, 98%

CAS No. :

[168098-94-0]

MDL No. :

MFCD30146121

Synonyms : 6-(3-Fluorobenzyloxy)-9H-purin-2-ylamine

Price and Availability
Pack Size	Price in USD	Quantity	Availability	Shipping Status
25MG	980.00	- +	Back Order	Estimated to Ship on 12.13.2024
100MG	2980.00	- +	Back Order	Estimated to Ship on 12.13.2024

Chemical Properties
Mol. Formula : C₁₂H₁₀FN₅O	Mol. Weight : 259.24
Appearance : Solid	Melting Point : Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : O6-Alkylguanine derivatives sensitize tumor cells to chloroethylnitrosourea (CENU) chemotherapy by inactivation of O6-methylguanine-DNA methyltransferase (MGMT), which repairs CENU-induced O6-alkylguanines in DNA. The O6-Fluorobenzylguanines with a fluoro-substitution at the 4-or 3-position of the benzyl group were comparable to O6-benzylguanine and were powerful MGMT inactivators.

References : Katsuyoshi. M. et. al.: .Life Sciences, 58(19), 303, 1996.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SL-678

Product Name : O6-(3-fluorobenzyl)guanine

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SL-678

O6-(3-fluorobenzyl)guanine, 98%

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