[156-83-2]    

MFCD00006097

Synonyms : 6-Chloropyrimidine-2,4-diamine

Applications : This is an impurity of Minoxidil (Minoxidil EP impurity B). A vasodilator medication known for its ability to slow or stop hair loss and promote hair regrowth. Minoxidil is an ATP-sensitive potassium (KATP) channel opener, a potent oral antihypertensive agent and a peripheral vasodilator that promotes vasodilation also affects hair growth.

References : Hadjipavlou-Litina D. et al.: Biochimie 95(7), 1437-49, 2013; Davies G. C. et al.: J. Invest Dermatol., 124(4), 686-94, 2005; Cohen R. L. et al.: J. Invest Dermatol., 82(1), 90-3, 1984.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.