SynInnova Laboratories Inc.

SL-7390

Des-4-fluorophenyl cabozantinib, >98%

CAS No. :

[849217-77-2]

Synonyms : 1-((4-((6,7-Dimethoxyquinolin-4-yl)oxy)phenyl)carbamoyl)cyclopropane-1-carboxylic acid

Price and Availability
Pack Size	Price in USD	Quantity	Availability	Shipping Status
25MG	550.00	- +	In Stock	Estimated to Ship on 01.06.2025
250MG	1550.00	- +	In Stock	Estimated to Ship on 01.06.2025

Chemical Properties
Mol. Formula : C₂₂H₂₀N₂O₆	Mol. Weight : 408.41
Appearance : White to Off-white solid	Melting Point : Not available
Solubility : DMSO
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an advanced key intermediate in the preparation of Cabozantinib and related analogs. An inhibitor of the tyrosine kinases c-Met and VEGFR2, and also inhibits AXL and RET. It is used to treat medullary thyroid cancer, renal cell carcinoma, and hepatocellular carcinoma.

References : You W. K. et al.: Cancer Res., 71(14), 4758-4768, 2011; Torres K. E. et al.: Clin Cancer Res., 17(12), 3943-3955, 2011; Yakes F. M. et al.: Mol Cancer Ther., 10(12), 2298-2308, 2011.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SL-7390

Product Name : Des-4-fluorophenyl cabozantinib

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Site is under construction and it will coming soon. Please contact us at sales@syninnova.com for COA. Thank you!

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Des-4-fluorophenyl cabozantinib, >98%

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