[1417699-82-1]    

Applications : This is an imidazole analog of ML-188 and exhibited equipotent profile to ML-188. It is a potent noncovalent small molecule inhibitor of the severe acute respiratory syndrome coronavirus (SARS-CoV) 3CL protease. ML-188 provides an excellent starting point for the further design and refinement of 3CLpro inhibitors that act by a noncovalent mechanism of action.

References : Jacobs J. et al.: J. Med. Chem., 56(2), 534−546, 2013.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.