[163222-33-1]    

Synonyms : (3R,4S)-1-(4-Fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one; SCH-58235

Applications : Ezetimibe is a potent, selective, cholesterol absorption inhibitor, used to lower cholesterol.

References : Clader J. W. et al.: J. Med Chem., 47(1), 1, 2004; During A. et al.: J. Nutr, 135(10), 2305, 2005; Davis H. R Jr. et al.: Arterioscler Thromb Vasc Biol, 21(12), 2032, 2001; Delaney W. E 4th, et al. Antimicrob Agents Chemother, 50(7), 2471, 2006; van Heek M. et al.: Br. J. Pharmacol., 134(2), 409, 2001; Davis H. R. et al.: J. Atheroscler Thromb., 14(3), 99, 2007.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.