MFCD30537602

Synonyms : 1E,6E)-1-(4-Hydroxy-3-methoxy-d₃-phenyl)-7-(3-methoxy-d₃-4-(prop-2-ynyloxy)phenyl)hepta-1,6 diene-3,5-dione

Applications : It is a deuterium labelled analogue of curcumin-monoalkyne, a biochemical for the snthesis of monofunctional curcumin derivatives via click chemistry usig [3+2] azide-alkyne cycloaddition reaction to make curcumin conjugates for therapeutic applications. It may also be possible to synthesize and screen a range of carbohydrate derivatives of curcumin to optimize brain uptake of the carbohydrate conjugates via the glucose transport mechanism.

References : Shi. W. et. al.: Org. Lett.,  9 , 5461, 2007.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.