SynInnova Laboratories Inc.

SI-1786

Apitolisib, 98% (HPLC)

CAS No. :

[1032754-93-0]

MDL No. :

MFCD20274520

Synonyms : (R)-1-(4-((2-(2-Aminopyrimidin-5-yl)-7-methyl-4-morpholinothieno[3,2-d]pyrimidin-6-yl)methyl)piperazin-1-yl)-2-hydroxypropan-1-one; GDC-0980; GNE 390; RG 7422

Price and Availability
Pack Size	Price in USD	Quantity	Availability	Shipping Status
10MG	150.00	- +	Back Order	Estimated to Ship on 01.19.2025
50MG	450.00	- +	Back Order	Estimated to Ship on 01.19.2025
100MG	750.00	- +	Back Order	Estimated to Ship on 01.19.2025

Chemical Properties
Mol. Formula : C₂₃H₃₀N₈O₃S	Mol. Weight : 498.6
Appearance : Solid	Melting Point : Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Apitolisib is a selective, potent, orally bioavailable Class I PI3 kinase and mTOR kinase (TORC1/2) inhibitor with IC₅₀s of 5 nM/27 nM/7 nM/14 nM for PI3Kα/PI3Kβ/PI3Kδ/PI3Kγ, and with a Ki of 17 nM for mTOR.

References : Sutherlin D. P. et al.: J. Med. Chem., 54 (21), 7579-7587, 2011; Wallin J. J. et al. Mol Cancer Ther., 10 (12), 2426-2436, 2011.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SI-1786

Product Name : Apitolisib

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SI-1786

Apitolisib, 98% (HPLC)

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