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SI-1786

Apitolisib, 98% (HPLC)

CAS No. : 
[1032754-93-0]    
MDL No. : 
MFCD20274520
Synonyms : (R)-1-(4-((2-(2-Aminopyrimidin-5-yl)-7-methyl-4-morpholinothieno[3,2-d]pyrimidin-6-yl)methyl)piperazin-1-yl)-2-hydroxypropan-1-one; GDC-0980; GNE 390; RG 7422

Price and Availability
Pack Size Price in USD Quantity Availability Shipping Status
10MG150.00 Back Order Estimated to Ship on 12.20.2024
50MG450.00 Back Order Estimated to Ship on 12.20.2024
100MG750.00 Back Order Estimated to Ship on 12.20.2024
Chemical Properties
C23H30N8O3S 498.6
Solid Not available
For Laboratory research use only, not for drug, household or other uses.
Applications : Apitolisib is a selective, potent, orally bioavailable Class I PI3 kinase and mTOR kinase (TORC1/2) inhibitor with IC50s of 5 nM/27 nM/7 nM/14 nM for PI3Kα/PI3Kβ/PI3Kδ/PI3Kγ, and with a Ki of 17 nM for mTOR.
References : Sutherlin D. P. et al.: J. Med. Chem., 54 (21), 7579-7587, 2011; Wallin J. J. et al. Mol Cancer Ther., 10 (12), 2426-2436, 2011.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SI-1786

Product Name : Apitolisib

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