SynInnova Laboratories Inc.

SI-5129

Sivelestat sodium, >98% (HPLC)

CAS No. :

[150374-95-1]

MDL No. :

MFCD08461731

Synonyms : Sodium (2-((4-(pivaloyloxy)phenyl)sulfonamido)benzoyl)glycinate; LY-544349 sodium; ONO-5046 sodium; EI-546 sodium

Price and Availability
Pack Size	Price in USD	Quantity	Availability	Shipping Status
10MG	120.00	- +	Back Order	Estimated to Ship on 01.20.2025
25MG	280.00	- +	Back Order	Estimated to Ship on 01.20.2025
50MG	550.00	- +	Back Order	Estimated to Ship on 01.20.2025
100MG	1050.00	- +	Back Order	Estimated to Ship on 01.20.2025
250MG	2250.00	- +	Back Order	Estimated to Ship on 01.20.2025

Chemical Properties
Mol. Formula : C₂₀H₂₁N₂NaO₇S	Mol. Weight : 456.44
Appearance : Solid	Melting Point : Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Sivelestat sodium is a competitive inhibitor of human neutrophil elastase, with an IC50 of 44 nM and a Ki of 200 nM. Sivelestat sodium has the potential for the study of acute lung injury/acute respiratory distress syndrome or disseminated intravascular coagulation in COVID-19.

References : Kawabata K. et al.: Biochem Biophys Res Commun., 177(2), 814-20, 1991; Toda Y. et al.: Int. J. Mol Med., 19(2), 237-43, 2007; Kono T. et al.: Mol Cell Biochem., 311(1-2), 87-92, 2008; Sahebnasagh A. et al.: J. Clin Pharm Ther., 45(6), 1515-1519, 2020.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SI-5129

Product Name : Sivelestat sodium

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