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SI-5129

Sivelestat sodium, >98% (HPLC)

CAS No. : 
[150374-95-1]    
MDL No. : 
MFCD08461731
Synonyms : Sodium (2-((4-(pivaloyloxy)phenyl)sulfonamido)benzoyl)glycinate; LY-544349 sodium; ONO-5046 sodium; EI-546 sodium

Price and Availability
Pack Size Price in USD Quantity Availability Shipping Status
10MG120.00
-
+
Back Order Estimated to Ship on 12.12.2024
25MG280.00
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+
Back Order Estimated to Ship on 12.12.2024
50MG550.00
-
+
Back Order Estimated to Ship on 12.12.2024
100MG1050.00
-
+
Back Order Estimated to Ship on 12.12.2024
250MG2250.00
-
+
Back Order Estimated to Ship on 12.12.2024
Chemical Properties
C20H21N2NaO7S 456.44
Solid Not available
For Laboratory research use only, not for drug, household or other uses.
Applications : Sivelestat sodium is a competitive inhibitor of human neutrophil elastase, with an IC50 of 44 nM and a Ki of 200 nM. Sivelestat sodium has the potential for the study of acute lung injury/acute respiratory distress syndrome or disseminated intravascular coagulation in COVID-19.
References : Kawabata K. et al.: Biochem Biophys Res Commun., 177(2), 814-20, 1991; Toda Y. et al.: Int. J. Mol Med., 19(2), 237-43, 2007; Kono T. et al.: Mol Cell Biochem., 311(1-2), 87-92, 2008; Sahebnasagh A. et al.: J. Clin Pharm Ther., 45(6), 1515-1519, 2020.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SI-5129

Product Name : Sivelestat sodium

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