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SI-5370

PF-06424439, >98% (HPLC)

CAS No. : 
[1469284-78-3]    
Synonyms : (R)-(1-(2-(1-(4-Chloro-1H-pyrazol-1-yl)cyclopropyl)-3H-imidazo[4,5-b]pyridin-5-yl)piperidin-3-yl)(pyrrolidin-1-yl)methanone

Price and Availability
Pack Size Price in USD Quantity Availability Shipping Status
5MGRequest QuoteBack Order Estimated to Ship on 12.06.2024
10MGRequest QuoteBack Order Estimated to Ship on 12.06.2024
25MGRequest QuoteBack Order Estimated to Ship on 12.06.2024
100MGRequest QuoteBack Order Estimated to Ship on 12.06.2024
250MGRequest QuoteBack Order Estimated to Ship on 12.06.2024

PF-06424439 is not in stock, can be available through custom synthesis. The estimated lead-time is 4-6 weeks. The product will be characterized by NMR and MS analysis. Purity (HPLC) is usually >98%. COA, QC data, SDS will be provided along with the product. For information on pricing and availability please contact us at sales@syninnova.com or submit the following Bulk Quote Request. We respond promptly. Thank You!

Chemical Properties
C22H26ClN7O 439.95
Solid Not available
For Laboratory research use only, not for drug, household or other uses.
Applications : PF-06424439 is an oral, potent and selective imidazopyridine diacylglycerol acyltransferase 2 (DGAT2) inhibitor with an IC50 of 14 nM. PF-06424439 is slowly reversible, time-dependent inhibitor, which inhibits DGAT2 in a noncompetitive mode with respect to the acyl-CoA substrate.
References : Futatsugi K. et al.: J. Med Chem., 58(18), 7173-85, 2015; Pabst B. et al.: Biochemistry 57(51), 6997-7010, 2018.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SI-5370

Product Name : PF-06424439

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Site is under construction and it will coming soon. Please contact us at sales@syninnova.com for COA. Thank you!

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