SynInnova Laboratories Inc.

SI-5371

PF-06424439 methanesulfonate, >98% (HPLC)

CAS No. :

[1469284-79-4]

MDL No. :

MFCD28137684

Synonyms : (R)-(1-(2-(1-(4-Chloro-1H-pyrazol-1-yl)cyclopropyl)-3H-imidazo[4,5-b]pyridin-5-yl)piperidin-3-yl)(pyrrolidin-1-yl)methanone methanesulfonate

Price and Availability
Pack Size	Price in USD	Quantity	Availability	Shipping Status
10MG	110.00	- +	Back Order	Estimated to Ship on 01.19.2025
25MG	250.00	- +	Back Order	Estimated to Ship on 01.19.2025
50MG	400.00	- +	Back Order	Estimated to Ship on 01.19.2025
100MG	600.00	- +	Back Order	Estimated to Ship on 01.19.2025
250MG	1100.00	- +	Back Order	Estimated to Ship on 01.19.2025

Chemical Properties
Mol. Formula : C₂₂H₂₆ClN₇O . CH₃SO₃H	Mol. Weight : 536.05
Appearance : Solid	Melting Point : Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : PF-06424439 is an oral, potent and selective imidazopyridine diacylglycerol acyltransferase 2 (DGAT2) inhibitor with an IC50 of 14 nM. PF-06424439 is slowly reversible, time-dependent inhibitor, which inhibits DGAT2 in a noncompetitive mode with respect to the acyl-CoA substrate.

References : Futatsugi K. et al.: J. Med Chem., 58(18), 7173-85, 2015; Pabst B. et al.: Biochemistry 57(51), 6997-7010, 2018.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SI-5371

Product Name : PF-06424439 methanesulfonate

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SI-5371

PF-06424439 methanesulfonate, >98% (HPLC)

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