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SI-5371

PF-06424439 methanesulfonate, >98% (HPLC)

CAS No. : 
[1469284-79-4]    
MDL No. : 
MFCD28137684
Synonyms : (R)-(1-(2-(1-(4-Chloro-1H-pyrazol-1-yl)cyclopropyl)-3H-imidazo[4,5-b]pyridin-5-yl)piperidin-3-yl)(pyrrolidin-1-yl)methanone methanesulfonate

Price and Availability
Pack Size Price in USD Quantity Availability Shipping Status
10MG110.00 Back Order Estimated to Ship on 12.06.2024
25MG250.00 Back Order Estimated to Ship on 12.06.2024
50MG400.00 Back Order Estimated to Ship on 12.06.2024
100MG600.00 Back Order Estimated to Ship on 12.06.2024
250MG1100.00 Back Order Estimated to Ship on 12.06.2024
Chemical Properties
C22H26ClN7O . CH3SO3H 536.05
Solid Not available
For Laboratory research use only, not for drug, household or other uses.
Applications : PF-06424439 is an oral, potent and selective imidazopyridine diacylglycerol acyltransferase 2 (DGAT2) inhibitor with an IC50 of 14 nM. PF-06424439 is slowly reversible, time-dependent inhibitor, which inhibits DGAT2 in a noncompetitive mode with respect to the acyl-CoA substrate.
References : Futatsugi K. et al.: J. Med Chem., 58(18), 7173-85, 2015; Pabst B. et al.: Biochemistry 57(51), 6997-7010, 2018.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SI-5371

Product Name : PF-06424439 methanesulfonate

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