SynInnova Laboratories Inc.

SI-5442

Abemaciclib, >98% (HPLC)

CAS No. :

[1231929-97-7]

MDL No. :

MFCD22665744

Synonyms : N-(5-((4-Ethylpiperazin-1-yl)methyl)pyridin-2-yl)-5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)pyrimidin-2-amine; LY-2835219

Price and Availability
Pack Size	Price in USD	Quantity	Availability	Shipping Status
10MG	80.00	- +	In Stock	Estimated to Ship on 12.06.2024
50MG	120.00	- +	In Stock	Estimated to Ship on 12.06.2024
100MG	150.00	- +	In Stock	Estimated to Ship on 12.06.2024
250MG	200.00	- +	In Stock	Estimated to Ship on 12.06.2024
500MG	350.00	- +	In Stock	Estimated to Ship on 12.06.2024

Chemical Properties
Mol. Formula : C₂₇H₃₂F₂N₈	Mol. Weight : 506.61
Appearance : Solid	Melting Point : Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Abemaciclib is a selective CDK4/6 inhibitor with IC50 values of 2 nM and 10 nM for CDK4 and CDK6, respectively. Abemaciclib can be used for the treatment of breast cancer.

References : Ku B. M. et al.: Oncotarget., 7(12), 14803-13, 2016; Yadav V. et al.: Mol Cancer Ther., 13(10), 2253-63, 2014; Gelbert L. M. et al.: Invest New Drugs., 32(5), 825-37, 2014.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SI-5442

Product Name : Abemaciclib

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SI-5442

Abemaciclib, >98% (HPLC)

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