SynInnova Laboratories Inc.

SI-5444

Abemaciclib-d₈, >98% (HPLC)

Isotopic Purity :

98 atom % D

CAS No. :

[2088650-53-5]

Synonyms : N-(5-((4-Ethylpiperazin-1-yl-d₈₎methyl)pyridin-2-yl)-5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)pyrimidin-2-amine; LY-2835219-d₈

Price and Availability
Pack Size	Price in USD	Quantity	Availability	Shipping Status
5MG	Request Quote	- +	Back Order	Estimated to Ship on 12.11.2024
10MG	Request Quote	- +	Back Order	Estimated to Ship on 12.11.2024
25MG	Request Quote	- +	Back Order	Estimated to Ship on 12.11.2024

Note: Abemaciclib-d8 is not in stock, can be available through custom synthesis. The estimated lead-time is 4-6 weeks. The product will be characterized by NMR and MS analysis. Purity (HPLC) is usually >98%. COA, QC data, SDS will be provided along with the product. For information on pricing and availability please contact us at sales@syninnova.com or submit the following Bulk Quote Request. We respond promptly. Thank You!

Chemical Properties
Mol. Formula : C₂₇H₂₄D₈F₂N₈	Mol. Weight : 514.65
Appearance : Solid	Melting Point : Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Abemaciclib-d8 is a deuterium labelled version analog of Abemaciclib, which is a selective CDK4/6 inhibitor with IC50 values of 2 nM and 10 nM for CDK4 and CDK6, respectively. Abemaciclib can be used for the treatment of breast cancer.

References : Ku B. M. et al.: Oncotarget., 7(12), 14803-13, 2016; Yadav V. et al.: Mol Cancer Ther., 13(10), 2253-63, 2014; Gelbert L. M. et al.: Invest New Drugs., 32(5), 825-37, 2014.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Your request for quote will also be accepted by e-mail at sales@syninnova.com or Fax: +1 780 485 2963.

Product ID : SI-5444

Product Name : Abemaciclib-d₈

Note : If you do not find your required compound in our catalogue, or not commercially available, please contact us, we will assist you to get your desired molecule. We only charge if we deliver to your satisfaction.

Site is under construction and it will coming soon. Please contact us at sales@syninnova.com for COA. Thank you!

Site is under construction and it will coming soon. Please contact us at sales@syninnova.com for HNMR. Thank you!

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SI-5446	Abemaciclib metabolite M18
SI-5448	Abemaciclib-d₈ metabolite M18
SI-5443	Abemaciclib-d₇
SI-5442	Abemaciclib
SI-5445	Abemaciclib mesylate
SI-5451	Abemaciclib metabolite M2
SI-5452	Abemaciclib-d6 metabolite M2
SI-5444	Abemaciclib-d₈
SI-5447	Abemaciclib metabolite M18 hydrochloride
SI-5450	Abemaciclib-d₈ metabolite M20
SI-5449	Abemaciclib metabolite M20

SL-3494	Lopinavir EP impurity K
SI-5444	Abemaciclib-d₈
SL-3495	Lopinavir EP impurity L
SL-2864	Barnidipine-d₅ hydrochloride
SI-4141	4-(3-Oxa-9-azabicyclo[3.3.1]nonan-9-yl)benzeneboronic acid pinacol ester
SL-3485	Lopinavir EP impurity B
SL-2869	(S)-3-Ethyl 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
SL-2933	Cyclophosphamide related compound D
SL-3489	Lopinavir EP impurity F
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SI-5444

Abemaciclib-d8, >98% (HPLC)

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