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SI-5586

Ulixertinib, >98% (HPLC)

CAS No. : 
[869886-67-9]    
MDL No. : 
MFCD22628898
Synonyms : (S)-4-(5-Chloro-2-(isopropylamino)pyridin-4-yl)-N-(1-(3-chlorophenyl)-2-hydroxyethyl)-1H-pyrrole-2-carboxamide; BVD-523; VRT752271

Price and Availability
Pack Size Price in USD Quantity Availability Shipping Status
5MG70.00 Back Order Estimated to Ship on 01.06.2025
10MG110.00 Back Order Estimated to Ship on 01.06.2025
50MG250.00 Back Order Estimated to Ship on 01.06.2025
100MG450.00 Back Order Estimated to Ship on 01.06.2025
250MG650.00 Back Order Estimated to Ship on 01.06.2025
Chemical Properties
C21H22Cl2N4O2 433.33
Solid Not available
For Laboratory research use only, not for drug, household or other uses.
Applications : Ulixertinib is a potent, orally active, highly selective, ATP-competitive and reversible covalent inhibitor of ERK1/2 kinases, with an IC50 of <0.3 nM against ERK2. Ulixertinib inhibits the phosphorylated ERK2 (pERK) and downstream kinase RSK (pRSK) in an A375 melanoma cell line.
References : Ward R. A. et al.: J Med Chem., 58(11), 4790-801, 2015; Kumar R. et al.: J. Pharm Biomed Anal., 125, 140-4, 2016; Ning C. et al.: Oncotarget., 8(27), 44295-44311, 2017.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SI-5586

Product Name : Ulixertinib

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