SynInnova Laboratories Inc.

SI-5666

Facinicline hydrochloride, >98% (HPLC)

CAS No. :

[677305-02-1]

Synonyms : N-((1s,4s)-Quinuclidin-3-yl)-1H-indazole-3-carboxamide hydrochloride; RG-3487 hydrochloride

Price and Availability
Pack Size	Price in USD	Quantity	Availability	Shipping Status
5MG	300.00	- +	Back Order	Estimated to Ship on 12.24.2024
10MG	500.00	- +	Back Order	Estimated to Ship on 12.24.2024
50MG	1350.00	- +	Back Order	Estimated to Ship on 12.24.2024
100MG	2050.00	- +	Back Order	Estimated to Ship on 12.24.2024

Chemical Properties
Mol. Formula : C₁₅H₁₈N₄O . HCl	Mol. Weight : 306.79
Appearance : Solid	Melting Point : Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Facinicline hydrochloride is an orally active nicotinic α7 receptor partial agonist, with a Ki of 6 nM for α7 human nAChR. Facinicline hydrochloride improves cognition and sensorimotor gating in rodents. Facinicline hydrochloride shows high affinity (antagonist) to 5-HT3Rs with a Ki value of 1.2 nM.

References : Wallace L. T. et al.: J. Pharmacol Exp Ther., 336(1), 242-53, 2011.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SI-5666

Product Name : Facinicline hydrochloride

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