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SI-5713

SB-334867 hydrochloride, >98% (HPLC)

CAS No. : 
[249889-64-3]    
MDL No. : 
MFCD16628181
Synonyms : 1-(2-Methylbenzo[d]oxazol-6-yl)-3-(1,5-naphthyridin-4-yl)urea hydrochloride

Price and Availability
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SB-334867 hydrochloride is not in stock, can be available through custom synthesis. The estimated lead-time is 4-6 weeks. The product will be characterized by NMR and MS analysis. Purity (HPLC) is usually >98%. COA, QC data, SDS will be provided along with the product. For information on pricing and availability please contact us at sales@syninnova.com or submit the following Bulk Quote Request. We respond promptly. Thank You!
Chemical Properties
C17H13N5O2 . HCl 355.78
Solid Not available
For Laboratory research use only, not for drug, household or other uses.
Applications : SB-334867 hydrochloride is an excellent, selective and blood–brain barrier permeable orexin-1 (OX1) receptor antagonist, shows selectivity over OX2 (pKb=7.4), 100-fold over 5-HT2B, 5-HT2C with pKi values of 5.4 and 5.3, respectively. SB-334867 hydrochloride reduces ethanol consumption and inhibits the acquisition of morphine-induced sensitization to locomotor activity in vivo.
References : Porter R. A. et al.: Bioorg Med Chem Lett., 11(14), 1907-10, 2001; Anderson R. I. et al.: Front Neurosci., 8, 33, 2014; Smart D. et al.: Br. J. Pharmacol., 132(6), 1179-82, 2001.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SI-5713

Product Name : SB-334867 hydrochloride

Note : If you do not find your required compound in our catalogue, or not commercially available, please contact us, we will assist you to get your desired molecule. We only charge if we deliver to your satisfaction.

Site is under construction and it will coming soon. Please contact us at sales@syninnova.com for COA. Thank you!

Site is under construction and it will coming soon. Please contact us at sales@syninnova.com for HNMR. Thank you!


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