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SI-5725

GSK-2656157, >98% (HPLC)

CAS No. : 
[1337532-18-9]    
Synonyms : 1-(5-(4-Amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-4-fluoroindolin-1-yl)-2-(6-(trifluoromethyl)pyridin-2-yl)ethan-1-one; GSK'157

Price and Availability
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5MGRequest Quote
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GSK-2656157 is not in stock, can be available through custom synthesis. The estimated lead-time is 4-6 weeks. The product will be characterized by NMR and MS analysis. Purity (HPLC) is usually >98%. COA, QC data, SDS will be provided along with the product. For information on pricing and availability please contact us at sales@syninnova.com or submit the following Bulk Quote Request. We respond promptly. Thank You!
Chemical Properties
C23H18F4N6O 470.43
Solid Not available
For Laboratory research use only, not for drug, household or other uses.
Applications : GSK-2656157 is a selective and ATP-competitive inhibitor of protein kinase R (PKR)-like endoplasmic reticulum kinase (PERK) with an IC50 of 0.9 nM. GSK2656157 was selected for advancement to preclinical development.
References : Atkins C. et al.: Cancer Res., 73(6), 1993-2002, 2013; Krishnamoorthy J. et al.: Cell Cycle 13(5), 801-6, 2014; Ando T. et al.: Immunopharmacol Immunotoxicol., 38(4), 298-302, 2016; Zhao Q. et al.: J. Neuroinflammation. 14(1), 104, 2017.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SI-5725

Product Name : GSK-2656157

Note : If you do not find your required compound in our catalogue, or not commercially available, please contact us, we will assist you to get your desired molecule. We only charge if we deliver to your satisfaction.

Site is under construction and it will coming soon. Please contact us at sales@syninnova.com for COA. Thank you!

Site is under construction and it will coming soon. Please contact us at sales@syninnova.com for HNMR. Thank you!


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