SynInnova Laboratories Inc.

SI-5731

Zetomipzomib, >98% (HPLC)

CAS No. :

[1629677-75-3]

Synonyms : (2S,3R)-N-((S)-3-(Cyclopent-1-en-1-yl)-1-((R)-2-methyloxiran-2-yl)-1-oxopropan-2-yl)-3-hydroxy-3-(4-methoxyphenyl)-2-((S)-2-(2-morpholinoacetamido) propanamido)propanamide; KZR-616

Price and Availability
Pack Size	Price in USD	Quantity	Availability	Shipping Status
5MG	Request Quote	- +	Back Order	Estimated to Ship on 12.22.2024
25MG	Request Quote	- +	Back Order	Estimated to Ship on 12.22.2024
100MG	Request Quote	- +	Back Order	Estimated to Ship on 12.22.2024
250MG	Request Quote	- +	Back Order	Estimated to Ship on 12.22.2024
500MG	Request Quote	- +	Back Order	Estimated to Ship on 12.22.2024

Note: Zetomipzomib is not in stock, can be available through custom synthesis. The estimated lead-time is 4-6 weeks. The product will be characterized by NMR and MS analysis. Purity (HPLC) is usually >98%. COA, QC data, SDS will be provided along with the product. For information on pricing and availability please contact us at sales@syninnova.com or submit the following Bulk Quote Request. We respond promptly. Thank You!

Chemical Properties
Mol. Formula : C₃₀H₄₂N₄O₈	Mol. Weight : 586.69
Appearance : Solid	Melting Point : Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Zetomipzomib is a first-in-class inhibitor of the immunoproteasome, selectively targets the LMP7 (IC50: 39/57 nM=hLMP7/mLMP7) and LMP2 (IC50: 131/179 nM=hLMP7/mLMP7) subunits of the immunoproteasome. Zetomipzomib has the potential for the research of multiple autoimmune diseases.

References : Johnson H. W. B. et al.: J. Med Chem., 61(24), 11127-11143, 2018; Muchamuel T. et al.: Annals of the Rheumatic Diseases 77, 685, 2018;
Xi J. et al.: Eur. J. Med Chem., 182, 111646, 2019.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Your request for quote will also be accepted by e-mail at sales@syninnova.com or Fax: +1 780 485 2963.

Product ID : SI-5731

Product Name : Zetomipzomib

Note : If you do not find your required compound in our catalogue, or not commercially available, please contact us, we will assist you to get your desired molecule. We only charge if we deliver to your satisfaction.

Site is under construction and it will coming soon. Please contact us at sales@syninnova.com for COA. Thank you!

Site is under construction and it will coming soon. Please contact us at sales@syninnova.com for HNMR. Thank you!

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SI-5731

Zetomipzomib, >98% (HPLC)

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