SynInnova Laboratories Inc.

SI-5732

Zetomipzomib maleate, >98% (HPLC)

CAS No. :

[2170983-62-5]

Synonyms : (2S,3R)-N-((S)-3-(Cyclopent-1-en-1-yl)-1-((R)-2-methyloxiran-2-yl)-1-oxopropan-2-yl)-3-hydroxy-3-(4-methoxyphenyl)-2-((S)-2-(2-morpholinoacetamido) propanamido)propanamide maleate; KZR-616 maleate

Price and Availability
Pack Size	Price in USD	Quantity	Availability	Shipping Status
5MG	1650.00	- +	Back Order	Estimated to Ship on 12.22.2024
10MG	2650.00	- +	Back Order	Estimated to Ship on 12.22.2024
25MG	5500.00	- +	Back Order	Estimated to Ship on 12.22.2024
50MG	8950.00	- +	Back Order	Estimated to Ship on 12.22.2024
100MG	13500.00	- +	Back Order	Estimated to Ship on 12.22.2024

Chemical Properties
Mol. Formula : C₃₀H₄₂N₄O₈ . C₄H₄O₄	Mol. Weight : 702.76
Appearance : Solid	Melting Point : Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Zetomipzomib maleate is a first-in-class inhibitor of the immunoproteasome, selectively targets the LMP7 (IC50: 39/57 nM=hLMP7/mLMP7) and LMP2 (IC50: 131/179 nM=hLMP7/mLMP7) subunits of the immunoproteasome. Zetomipzomib has the potential for the research of multiple autoimmune diseases.

References : Johnson H. W. B. et al.: J. Med Chem., 61(24), 11127-11143, 2018; Muchamuel T. et al.: Annals of the Rheumatic Diseases 77, 685, 2018;
Xi J. et al.: Eur. J. Med Chem., 182, 111646, 2019.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SI-5732

Product Name : Zetomipzomib maleate

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Zetomipzomib maleate, >98% (HPLC)

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