[155320-20-0]    

MFCD09750030

Synonyms : 1-Isothiocyanato-4-[(S)-methylsulfinyl]butane; (+)-Sulforaphane

Applications : (S)-Sulforaphane is a antitumor agent that occurs naturally in broccoli. (S)-Sulforaphane is a potent, selective inducer of phase II detoxification enzymes with anticarcinogenic properties. (S)-Sulforaphane is found to inhibit chemically induced mammary tumor formation in rats. (S)-Sulforaphane is a non-competitive antagonist of Aryl Hydrocarbon Receptor.

References : Zhang. Y. et al.: Proc. Natl. Acad. Sci. USA, 89, 2399,1992; Shikita, M. et al.: Biochem. J., 341, 725,1999; Wittich S. et al.: J. Med. Chem., 45, 3296, 2002: Lee, J., et al.: Cancer Lett., 224, 171, 2005.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.