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MFCD00198068

Synonyms : 1-Isothiocyanato-4-(methylsulfinyl)-butane; 4-Methylsulfinylbutyl isothiocyanate; R,S-Sulforaphane; Sulforaphan

Applications : R,S-Sulforaphane is a synthetic isothiocyanate. R-Sulforaphane is the naturally-occurring isomer, found in broccoli. This compound exhibits antioxidative, neuroprotective, anti-inflammatory, anti-atherosclerotic, neuromodulatory, cardioprotective, anticoagulant, antibiotic, anticancer chemotherapeutic, and chemopreventive activities; research suggests that the R-isomer may be more bioactive than the S-isomer. R,S-Sulforaphane induces activity and expression of phase II enzymes, inhibits the aryl hydrocarbon receptor, and downregulates expression of HDACs and STAT5.

References : Lee J.H. et al.: Neuroscience. Oct 10, 278, 31-39, 2014; Zhang R. et al.: Int. J Mol Sci. Aug 18,15 (8),14396-410, 2014; Nallasamy P. et al.: J Nutr Biochem. Aug, 25(8), 824-833, 2014; Pinz S. et al.: PLoS One. Jun 9, 9 (6), e99391, 2014.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.