[289711-21-3] of the free acid

Synonyms : Sodium N5-((2R)-1-((carboxylatomethyl)amino)-3-(((4-(methylsulfinyl)butyl)carbamothioyl)thio)-1-oxopropan-2-yl)-L-glutaminate; SFN-GSH sodium salt

Applications : It is a conjugate of Sulforaphane and Glutathione. In vivo, sulforaphane conjugates with glutathione during metabolism. In animal models of prostate cancer, this conjugate displays antioxidative and anticancer chemotherapeutic activities, increasing levels of heme oxygenase 1 (HO-1), Nrf2, activated caspase 3, cleaved PARP, and Bax, decreasing levels of Keap1, Bcl-xl, 4E-BP1, mTOR, and cyclin D1, and slowing tumor growth.

References : Keum Y.S .et al.: Pharm Res. Oct, 26 (10), 2324-2331, 2009; PMID: 19669099.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.