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SL-2474 

Apremilast-d3, 98% (CP)

Isotopic Purity : 
99 atom % D
Synonyms : (S)-2-[1-(3-Ethoxy-(4-methoxy-d3)-phenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione; (S)-N-(2-(1-(3-Ethoxy-(4-methoxy-d3)-phenyl)-2-(methylsplfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide; CC 10004-d3

Price and Availability
Pack Size Price in USD Quantity Availability Shipping Status
5MG980.00 In Stock Estimated to Ship on 12.10.2024
10MG1880.00 In Stock Estimated to Ship on 12.10.2024
Chemical Properties
C22H21D3N2O7S 463.52
Off-white solid Not available
For Laboratory research use only, not for drug, household or other uses.
Applications : Apremilast-d3 is a deuterium labelled analog. A novel phosphodiesterase 4 (PDE4) inhibitor, regulates inflammation through multiple cAMP downstream effectors. Apremilast inhibits PDE4 with an IC50 of 74 nM using 1 μM cAMP as substrate.
References : Perez-Aso M. et al.: Arthritis Res Ther.,17, 249, 2015; Chen L.G. et al.: J. Chromatogr Sci. 54 (8), 1336-40, 2016.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SL-2474

Product Name : Apremilast-d3

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