SynInnova Laboratories Inc.

SL-2479

Apremilast EP impurity F, 98%

Synonyms : 2-Amino-6-((1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)carbamoyl)benzoic acid; rac-N-Deacetyl-2-carboxy-(seco-phthalimido) apremilast

Price and Availability
Pack Size	Price in USD	Quantity	Availability	Shipping Status
5MG	280.00	- +	Back Order	Estimated to Ship on 12.06.2024
10MG	400.00	- +	Back Order	Estimated to Ship on 12.06.2024
25MG	850.00	- +	Back Order	Estimated to Ship on 12.06.2024

Chemical Properties
Mol. Formula : C₂₀H₂₄N₂O₇S	Mol. Weight : 436.48
Appearance : Solid	Melting Point : Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : 2-Amino-6-((1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)carbamoyl)benzoic acid is an impurity of Apremilast (Apremilast EP impurity F). A novel phosphodiesterase 4 (PDE4) inhibitor, regulates inflammation through multiple cAMP downstream effectors. Apremilast inhibits PDE4 with an IC₅₀ of 74 nM using 1 μM cAMP as substrate.

References : Perez-Aso M. et al.: Arthritis Res Ther.,17, 249, 2015; Chen L.G. et al.: J. Chromatogr Sci. 54 (8), 1336-40, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SL-2479

Product Name : Apremilast EP impurity F

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