SynInnova Laboratories Inc.

SL-2480

Apremilast EP impurity H, 98%

CAS No. :

[253168-94-4]

MDL No. :

MFCD27665207

Synonyms : 1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethan-1-amine

Price and Availability
Pack Size	Price in USD	Quantity	Availability	Shipping Status
1G	50.00	- +	In Stock	Estimated to Ship on 12.10.2024
5G	160.00	- +	In Stock	Estimated to Ship on 12.10.2024

Chemical Properties
Mol. Formula : C₁₂H₁₉NO₄S	Mol. Weight : 273.35
Appearance : Solid	Melting Point : Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : 1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethan-1-amine is an impurity of Apremilast (Apremilast EP impurity H). A novel phosphodiesterase 4 (PDE4) inhibitor, regulates inflammation through multiple cAMP downstream effectors. Apremilast inhibits PDE4 with an IC₅₀ of 74 nM using 1 μM cAMP as substrate.

References : Perez-Aso M. et al.: Arthritis Res Ther.,17, 249, 2015; Chen L.G. et al.: J. Chromatogr Sci. 54 (8), 1336-40, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SL-2480

Product Name : Apremilast EP impurity H

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SL-2477	Apremilast EP impurity D
SL-2498	Apremilast impurity 16
SL-2491	Apremilast R-isomer
SL-2476	Apremilast EP impurity C
SL-2490	Desacetyl apremilast
SL-2484	Apremilast impurity 4
SL-2492	Apremilast dimer
SL-2485	Apremilast impurity 5
SL-2483	Apremilast impurity 3
SL-2489	Apremilast impurity 9
SL-2495	Apremilast impurity 13
SL-2479	Apremilast EP impurity F

SL-2480	Apremilast EP impurity H
SL-2493	Apremilast impurity 11
SL-2483	Apremilast impurity 3
SI-3473	4-Ethoxy-3-methoxybenzonitrile
SI-5954	USC-087
SL-2797	Apremilast impurity RS-7
SI-5608	Zenarestat
SL-2479	Apremilast EP impurity F
SL-2494	Apremilast impurity 12
SL-2482	Apremilast impurity 2
SI-3474	(E)-1-(4-Ethoxy-3-methoxyphenyl)-2-(methylsulfonyl)ethenamine
SL-2476	Apremilast EP impurity C

SL-2480

Apremilast EP impurity H, 98%

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