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MFCD06658574

Synonyms : Diethylnitrosamine-d₁₀

Applications : N-Nitrosodiethylamine-d10 is a labelled analog of N-Nitrosodiethylamine, which is a widely occurring nitrosamine that is one of the most important environmental carcinogens primarily inducing tumors of liver. NDMA and NDEA were found as an impurity in generic versions of valsartan, losartan and irbesartan.

References : Oda Y. et al.: Mutation Research, Genetic Toxicology and Environmental Mutagenesis, 584, 1, 2005; Yamazaki H. et al.: Carcinogenesis, 13, 1789, 1992; Chem. and Eng. News, p.5, Feb. 25, 2019.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.