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SL-3363

(S)-Ibrutinib-d5, 98% (CP)

Isotopic Purity : 
98 atom % D
Synonyms : (S)-1-(3-(4-Amino-3-((4-phenoxy-d5)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one

Price and Availability
Pack Size Price in USD Quantity Availability Shipping Status
5MG680.00 Back Order Estimated to Ship on 12.23.2024
10MG1280.00 Back Order Estimated to Ship on 12.23.2024
Chemical Properties
C25H19D5N6O2 445.53
Solid Not available
For Laboratory research use only, not for drug, household or other uses.
Applications : (S)-Ibrutinib-d5 is a deuterium labelled an opposite enantiomer of Ibrutinib, which is a selective, irreversible Bruton's tyrosine kinase (Btk) inhibitor, used to treat B cell cancers like mantle cell lymphoma, chronic lymphocytic leukemia, and Waldenström's macroglobulinemia.
References : Honigberg L. A. et al.: Proc. Nat. Acad. Sci., U S A. 107 (29),13075-13080, 2010; Herman S.E. et al.: Blood. 117 (23), 6287-6296, 2011; Chang B.Y. et al.: Arthritis Res Ther., 13(4), R115, 2011; Wu H. et al.: Sci Rep., 7 (1), 466, 2017.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SL-3363

Product Name : (S)-Ibrutinib-d5

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