SynInnova Laboratories Inc.

SL-3370

4-Hydroxy ibrutinib, 98%

CAS No. :

[1288339-18-3]

Synonyms : (R)-1-(3-(4-Amino-3-(4-(4-hydroxyphenoxy)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one

Price and Availability
Pack Size	Price in USD	Quantity	Availability	Shipping Status
5MG	880.00	- +	Back Order	Estimated to Ship on 12.23.2024
10MG	1680.00	- +	Back Order	Estimated to Ship on 12.23.2024

Chemical Properties
Mol. Formula : C₂₅H₂₄N₆O₃	Mol. Weight : 456.50
Appearance : Solid	Melting Point : Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : 4-Hydroxy ibrutinib is an impurity of Ibrutinib, which is a selective, irreversible Bruton's tyrosine kinase (Btk) inhibitor, used to treat B cell cancers like mantle cell lymphoma, chronic lymphocytic leukemia, and Waldenström's macroglobulinemia.

References : Honigberg L. A. et al.: Proc. Nat. Acad. Sci., U S A. 107 (29),13075-13080, 2010; Herman S.E. et al.: Blood. 117 (23), 6287-6296, 2011; Chang B.Y. et al.: Arthritis Res Ther., 13(4), R115, 2011; Wu H. et al.: Sci Rep., 7 (1), 466, 2017.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SL-3370

Product Name : 4-Hydroxy ibrutinib

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SI-3952	N-Desacryloyl ibrutinib
SL-3362	(S)-Ibrutinib
SL-3365	Ibrutinib dimer
SL-3363	(S)-Ibrutinib-d₅
SL-3366	Ibrutinib dimer impurity
SL-3356	N6-Acryloyl ibrutinib
SL-3370	4-Hydroxy ibrutinib
SL-2249	Dihydrodiol Ibrutinib-d₅
SI-3949	5-Amino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile
SL-3371	Ibrutinib methoxy impurity
SL-3368	Ibrutinib M34

SL-3370	4-Hydroxy ibrutinib
SL-7613	Ceritinib dimer impurity
SI-3490	1-Chloro-5-isopropoxy-2-methyl-4-nitrobenzene
SI-1591	4-Chloro-7-methoxyquinoline-6-carboxamide
SL-4753	Pantoprazole impurity 23
SL-4757	Pantoprazole impurity 27
SI-124	Methyl 2,4,5-trimethoxybenzoylacetate
SL-4721	Pantoprazole
SL-3356	N6-Acryloyl ibrutinib
SL-3357	N1-(2-Carboxyethyl) ibrutinib
SL-4756	Pantoprazole impurity 26
SL-4730	Pantoprazole EP impurity B

SL-3370

4-Hydroxy ibrutinib, 98%

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