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SL-2248 

Dihydrodiol Ibrutinib, 98%

CAS No. : 
[1226872-27-0]    
Synonyms : 1-((R)-3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-2,3-dihydroxypropan-1-one; PCI 45227

Price and Availability
Pack Size Price in USD Quantity Availability Shipping Status
5MG180.00
-
+
In Stock Estimated to Ship on 01.11.2025
10MG350.00
-
+
In Stock Estimated to Ship on 01.11.2025
25MG800.00
-
+
In Stock Estimated to Ship on 01.11.2025
50MG1500.00
-
+
In Stock Estimated to Ship on 01.11.2025
Chemical Properties
C25H26N6O4 474.51
Off-white solid Not available
For Laboratory research use only, not for drug, household or other uses.
Applications : Dihydrodiol Ibrutinib is a metabolite of Ibrutinib, which is a selective, irreversible Btk inhibitor with IC50 value of 0.5 nM.
References : Honigberg L. A. et al.: Proc. Nat. Acad. Sci., U S A. 107 (29),13075-13080, 2010; Herman S.E. et al.: Blood. 117 (23), 6287-6296, 2011; Chang B.Y. et al.: Arthritis Res Ther., 13(4), R115, 2011; Wu H. et al.: Sci Rep., 7 (1), 466, 2017.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SL-2248

Product Name : Dihydrodiol Ibrutinib

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