SynInnova Laboratories Inc.

SL-3517

N-Despropyl-macitentan-d₄, >95% (HPLC)

Isotopic Purity :

98 atom % D

Synonyms : N-[5-(4-Bromophenyl)-6-[2-[(5-bromo-2-pyrimidinyl)oxy]ethoxy-d₄]-4-pyrimidinyl]-sulfamide; ACT-132577-d₄

Price and Availability
Pack Size	Price in USD	Quantity	Availability	Shipping Status
5MG	980.00	- +	In Stock	Estimated to Ship on 01.11.2025
10MG	1680.00	- +	In Stock	Estimated to Ship on 01.11.2025

Chemical Properties
Mol. Formula : C₁₆H₁₀D₄Br₂N₆O₄S	Mol. Weight : 550.22
Appearance : White solid	Melting Point : Not available
Solubility : DMSO
For Laboratory research use only, not for drug, household or other uses.

Applications : N-Despropyl-macitentan-d4 is a deuterium labelled an active metabolite of Macitentan, which is an orally active, non-peptide endothelin receptor antagonist for the treatment of idiopathic pulmonary fibrosis and pulmonary arterial hypertension.

References : Iglarz M. et al. J. Pharmacol Exp Ther., 327(3), 736-745, 2008; Sen S. et al.: Life Sci., 91(13-14), 658-668, 2012; Kim S. J. et al.: Neoplasia., 13(2), 167-179, 2011.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SL-3517

Product Name : N-Despropyl-macitentan-d₄

Note : If you do not find your required compound in our catalogue, or not commercially available, please contact us, we will assist you to get your desired molecule. We only charge if we deliver to your satisfaction.

Site is under construction and it will coming soon. Please contact us at sales@syninnova.com for COA. Thank you!

Site is under construction and it will coming soon. Please contact us at sales@syninnova.com for HNMR. Thank you!

Related Products

SI-3964	O-Desbromo-pyrimidinyl-macitentan
SL-3527	Macitentan impurity 9
SL-3535	Macitentan impurity 15
SL-3519	N-[5-(4-Bromophenyl)-6-chloro-4-pyrimidinyl]-N’-propylsulfamide
SL-3538	Macitentan impurity 18
SL-3529	Macitentan impurity 11
SL-2719	Macitentan-d₄
SL-3526	Macitentan impurity 8
SL-3536	Macitentan impurity 16
SL-3517	N-Despropyl-macitentan-d₄
SL-3533	Macitentan impurity 13
SL-3537	Macitentan impurity 17

SL-3517	N-Despropyl-macitentan-d₄
SL-3531	Macitentan hydroxy N-propyl impurity
SL-3524	Macitentan impurity 6
SI-3964	O-Desbromo-pyrimidinyl-macitentan
SL-3536	Macitentan impurity 16
SL-3526	Macitentan impurity 8
SL-3294	Frovatriptan
SL-6804	D-delta-Tocopherol
SL-1603	2-Ethyl-3,4,5,6-tetrahydropyridine-d₃
SA-683	2,4,6-Trichlorophenylhydrazine
SI-3091	2-(Benzyloxy)-3-(chloromethyl)-4,6-dimethylpyridine
SL-3518	Macitentan dimer

SL-3517

N-Despropyl-macitentan-d4, >95% (HPLC)

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