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SL-3517 

N-Despropyl-macitentan-d4, >95% (HPLC)

Isotopic Purity : 
98 atom % D
Synonyms : N-[5-(4-Bromophenyl)-6-[2-[(5-bromo-2-pyrimidinyl)oxy]ethoxy-d4]-4-pyrimidinyl]-sulfamide; ACT-132577-d4

Price and Availability
Pack Size Price in USD Quantity Availability Shipping Status
5MG980.00 In Stock Estimated to Ship on 12.10.2024
10MG1680.00 In Stock Estimated to Ship on 12.10.2024
Chemical Properties
C16H10D4Br2N6O4S 550.22
White solid Not available
DMSO
For Laboratory research use only, not for drug, household or other uses.
Applications : N-Despropyl-macitentan-d4 is a deuterium labelled an active metabolite of Macitentan, which is an orally active, non-peptide endothelin receptor antagonist for the treatment of idiopathic pulmonary fibrosis and pulmonary arterial hypertension.
References : Iglarz M. et al. J. Pharmacol Exp Ther., 327(3), 736-745, 2008; Sen S. et al.: Life Sci., 91(13-14), 658-668, 2012; Kim S. J. et al.: Neoplasia., 13(2), 167-179, 2011.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SL-3517

Product Name : N-Despropyl-macitentan-d4

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