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SI-3964

O-Desbromo-pyrimidinyl-macitentan, 98%

CAS No. : 
[1393813-43-8]    
MDL No. : 
MFCD25372066
Synonyms : N-(5-(4-Bromophenyl)-6-(2-hydroxyethoxy)pyrimidin-4-yl)propane-1-sulfamide

Price and Availability
Pack Size Price in USD Quantity Availability Shipping Status
10MG120.00 Back Order Estimated to Ship on 12.06.2024
25MG300.00 Back Order Estimated to Ship on 12.06.2024
50MG550.00 Back Order Estimated to Ship on 12.06.2024
100MG980.00 Back Order Estimated to Ship on 12.06.2024
Chemical Properties
C15H19BrN4O4S 431.30
Off-white solid Not available
For Laboratory research use only, not for drug, household or other uses.
Applications : This is an advanced key intermediate in the preparation of Macitentan and related analogs, which is an orally active, non-peptide endothelin receptor antagonist for the treatment of idiopathic pulmonary fibrosis and pulmonary arterial hypertension.
References : Iglarz M. et al. J. Pharmacol Exp Ther., 327(3), 736-745, 2008; Sen S. et al.: Life Sci., 91(13-14), 658-668, 2012; Kim S. J. et al.: Neoplasia., 13(2), 167-179, 2011.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SI-3964

Product Name : O-Desbromo-pyrimidinyl-macitentan

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