SynInnova Laboratories Inc.

SI-3964

O-Desbromo-pyrimidinyl-macitentan, 98%

CAS No. :

[1393813-43-8]

MDL No. :

MFCD25372066

Synonyms : N-(5-(4-Bromophenyl)-6-(2-hydroxyethoxy)pyrimidin-4-yl)propane-1-sulfamide

Price and Availability
Pack Size	Price in USD	Quantity	Availability	Shipping Status
10MG	120.00	- +	Back Order	Estimated to Ship on 12.24.2024
25MG	300.00	- +	Back Order	Estimated to Ship on 12.24.2024
50MG	550.00	- +	Back Order	Estimated to Ship on 12.24.2024
100MG	980.00	- +	Back Order	Estimated to Ship on 12.24.2024

Chemical Properties
Mol. Formula : C₁₅H₁₉BrN₄O₄S	Mol. Weight : 431.30
Appearance : Off-white solid	Melting Point : Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an advanced key intermediate in the preparation of Macitentan and related analogs, which is an orally active, non-peptide endothelin receptor antagonist for the treatment of idiopathic pulmonary fibrosis and pulmonary arterial hypertension.

References : Iglarz M. et al. J. Pharmacol Exp Ther., 327(3), 736-745, 2008; Sen S. et al.: Life Sci., 91(13-14), 658-668, 2012; Kim S. J. et al.: Neoplasia., 13(2), 167-179, 2011.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SI-3964

Product Name : O-Desbromo-pyrimidinyl-macitentan

Note : If you do not find your required compound in our catalogue, or not commercially available, please contact us, we will assist you to get your desired molecule. We only charge if we deliver to your satisfaction.

Site is under construction and it will coming soon. Please contact us at sales@syninnova.com for COA. Thank you!

Site is under construction and it will coming soon. Please contact us at sales@syninnova.com for HNMR. Thank you!

Related Products

SL-3521	Macitentan impurity 2
SL-3518	Macitentan dimer
SL-3519	N-[5-(4-Bromophenyl)-6-chloro-4-pyrimidinyl]-N’-propylsulfamide
SI-3964	O-Desbromo-pyrimidinyl-macitentan
SL-3531	Macitentan hydroxy N-propyl impurity
SL-3535	Macitentan impurity 15
SL-3516	N-Despropyl-macitentan
SL-3527	Macitentan impurity 9
SL-3538	Macitentan impurity 18
SL-2719	Macitentan-d₄
SL-3517	N-Despropyl-macitentan-d₄
SL-3525	Macitentan impurity 7

SI-3964	O-Desbromo-pyrimidinyl-macitentan
SL-1347	Olaparib-d₄
sl-6021	GS-443902
SL-3533	Macitentan impurity 13
SI-3537	2-Fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoic acid
SI-3953	Istradefylline
SI-1491	N-(4-Methoxybenzyl)isoxazol-3-amine
SL-1606	HDAC-IN-4
SL-3530	Macitentan impurity 12
SI-4266	(6R,7R)-7-Amino-3-((4-(1-methylpyridin-1-ium-4-yl)thiazol-2-yl)thio)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
SL-3522	Macitentan impurity 3
SL-1352	4-[4-Fluoro-3-(piperazine-1-carbonyl)benzyl]phthalazin-1(2H)-one

SI-3964

O-Desbromo-pyrimidinyl-macitentan, 98%

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