SynInnova Laboratories Inc.

SL-3610

Nilotinib impurity 11, 98%

CAS No. :

[916975-92-3]

MDL No. :

MFCD18800877

Synonyms : 4-Methyl-1-(3-nitro-5-(trifluoromethyl)phenyl)-1H-imidazole

Price and Availability
Pack Size	Price in USD	Quantity	Availability	Shipping Status
1G	500.00	- +	Back Order	Estimated to Ship on 01.25.2025
5G	1800.00	- +	Back Order	Estimated to Ship on 01.25.2025

Chemical Properties
Mol. Formula : C₁₁H₈F₃N₃O₂	Mol. Weight : 271.20
Appearance : Pale yellow solid	Melting Point : Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Nilotinib (Nilotinib impurity 11), which is a selective Bcr-Abl tyrosine kinase inhibitor, for the potential treatment of various leukemias, including chronic myeloid leukemia (CML).

References : Weisberg E. et al. Blood, 109(5), 2112-2120, 2007; Liu Y. et al.: J. Hepatol, 55(3), 612-625, 2011; Hochhaus A. et al.: Cell Cycle, 10(2), 250-260, 2011; Ammoun S. et al.: Neuro Oncol., 13(7), 759-766, 2011; Rhee C. K. et al.: Respiration., 82(3), 273-287, 2011; Weisberg E. et al. Cancer Cell, 7(2), 129-141, 2005.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SL-3610

Product Name : Nilotinib impurity 11

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SL-3597	Nilotinib EP impurity H
SL-3616	2-Amino-4-(3-pyridyl)pyrimidine
SL-3594	Nilotinib EP impurity E
SL-3615	3-Amino-4-methylacetophenone
SL-3590	Nilotinib hydrochloride
SL-3617	2-Amino-4-(2-pyridyl)pyrimidine
SL-3599	Nilotinib N-oxide
SL-3613	Nilotinib impurity 15
SL-3598	3-Iodo-4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)benzamide
SL-3608	Nilotinib impurity 9
SL-3600	Nilotinib impurity 1

SL-3610	Nilotinib impurity 11
SL-4076	Solifenacin ethyl ester
SL-2904	Cilastatin EP impurity C
SL-4072	Solifenacin EP impurity H
SL-3599	Nilotinib N-oxide
SL-2460	3-Bromo vortioxetine
SL-2223	Fluphenazine-d₆ dihydrochloride
SL-2226	2-(4-(3-(2’,8-Bis(trifluoromethyl)-10H-[3,10’-biphenothiazin]-10-yl)propyl)piperazin-1-yl)ethanol
SL-7263	Bendamustine monohydroxy isopropyl ester
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SL-3610

Nilotinib impurity 11, 98%

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