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SL-2594

Bosentan-d4 USP related compound C, 98% (HPLC)

Synonyms : N,Nā€™-[1,2-Ethanediylbis[oxy[5-(2-methoxyphenoxy)[2,2ā€™-bipyrimidine]-6,4-diyl]]]bis[4-(1,1-dimethylethyl)-benzenesulfonamide-d4

Price and Availability
Pack Size Price in USD Quantity Availability Shipping Status
5MG1200.00 Back Order Estimated to Ship on 01.20.2025
10MG2200.00 Back Order Estimated to Ship on 01.20.2025
Chemical Properties
C52H48D4N10O10S2 1045.18
Solid Not available
For Laboratory research use only, not for drug, household or other uses.
Applications : This is a deuterium labelled impurity of Bosentan, which is a competitive and dual antagonist of endothelin-1 (ET) for the ETA and ETB receptors with Ki of 4.7 nM and 95 nM in human SMC, respectively.
References : Dhillon S. et al.: Am J. Cardiovasc Drugs 9 (5), 331-350, 2009; Akamata K. et al. Arthritis Res Ther. 16 (2), R86, 2014; Iglarz M. et al. Life Sci. 118 (2), 333-339, 2014; Son G. Y. et al. PLoS One 11(12), e0167713, 2016.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SL-2594

Product Name : Bosentan-d4 USP related compound C

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