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SL-2584 

Bosentan-13C2, d4, >99% (HPLC)

Isotopic Purity : 
98 atom % D and 99 atom % 13C
Related CAS No. : 
[150726-52-6] of the unlabelled compound
Synonyms : 4-(tert-Butyl)-N-(6-(2-hydroxyethoxy-13C2, d4)-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)benzenesulfonamide; Benzenesulfonamide-13C2, d4; Tracleer-13C2 d4; Actelion-13C2, d4; Ro 47-0203/039-13C, d4; Ro 47-0203-13C, d4

Price and Availability
Pack Size Price in USD Quantity Availability Shipping Status
5MG880.00 In Stock Estimated to Ship on 11.19.2024
10MG1680.00 In Stock Estimated to Ship on 11.19.2024
Chemical Properties
C2513C2H25D4N5O6S 557.62
Light yellow solid Not available
DCM, MeOH
For Laboratory research use only, not for drug, household or other uses.
Applications : Bosentan-13C2, d4 is a mixed labelled analog, which is a competitive and dual antagonist of endothelin-1 (ET) for the ETA and ETB receptors with Ki of 4.7 nM and 95 nM in human SMC, respectively.
References : Dhillon S. et al.: Am J. Cardiovasc Drugs 9 (5), 331-350, 2009; Akamata K. et al. Arthritis Res Ther. 16 (2), R86, 2014; Iglarz M. et al. Life Sci. 118 (2), 333-339, 2014; Son G. Y. et al. PLoS One 11(12), e0167713, 2016.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SL-2584

Product Name : Bosentan-13C2, d4

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