SynInnova Laboratories Inc.

SL-2585

Desmethyl bosentan, 98% (HPLC)

CAS No. :

[253688-61-8]

MDL No. :

MFCD09840361

Synonyms : 4-(tert-Butyl)-N-(6-(2-hydroxyethoxy)-5-(2-hydroxyphenoxy)-[2,2'-bipyrimidin]-4-yl)benzenesulfonamide; Bosentan O-desmethyl impurity; Ro 47-8634

Price and Availability
Pack Size	Price in USD	Quantity	Availability	Shipping Status
5MG	680.00	- +	Back Order	Estimated to Ship on 01.20.2025
10MG	1280.00	- +	Back Order	Estimated to Ship on 01.20.2025

Chemical Properties
Mol. Formula : C₂₆H₂₇N₅O₆S	Mol. Weight : 537.59
Appearance : Yellow solid	Melting Point : Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Desmethyl bosentan is a metabolite of Bosentan, which is a competitive and dual antagonist of endothelin-1 (ET) for the ET_Aand ET_B receptors with Ki of 4.7 nM and 95 nM in human SMC, respectively.

References : Dhillon S. et al.: Am J. Cardiovasc Drugs 9 (5), 331-350, 2009; Akamata K. et al. Arthritis Res Ther. 16 (2), R86, 2014; Iglarz M. et al. Life Sci. 118 (2), 333-339, 2014; Son G. Y. et al. PLoS One 11(12), e0167713, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

To receive price and delivery information on larger quantities, please complete the form below and we will respond promptly.

If you login prior to completion of the form, your contact information will automatically populate.

Your request for quote will also be accepted by e-mail at sales@syninnova.com or Fax: +1 780 485 2963.

Product ID : SL-2585

Product Name : Desmethyl bosentan

Note : If you do not find your required compound in our catalogue, or not commercially available, please contact us, we will assist you to get your desired molecule. We only charge if we deliver to your satisfaction.

Site is under construction and it will coming soon. Please contact us at sales@syninnova.com for COA. Thank you!

Site is under construction and it will coming soon. Please contact us at sales@syninnova.com for HNMR. Thank you!

Related Products

SL-2596	Bosentan USP related compound A
SL-2592	Hydroxy desmethyl bosentan-d₄
SL-2594	Bosentan-d₄ USP related compound C
SL-2813	Bosentan monoacid impurity
SL-2586	Desmethyl bosentan-d₄
SL-2585	Desmethyl bosentan
SL-2597	Bosentan USP related compound D
SL-2590	Hydroxy bosentan-d₆
SL-2595	Bosentan impurity
SL-2587	O-Deshydroxyethyl bosentan
SL-2583	Bosentan-d₄
SL-2812	Bosentan diacid impurity

SL-2585	Desmethyl bosentan
SL-549	(R)-N-(2-(3-(2-(7-(dimethylamino)-2-oxo-2H-chromen-4-yl) acetamido)propoxy)ethyl)-2,4-dihydroxy-3,3-dimethyl butanamide
SL-1854	Tenofovir disoproxil
SL-6071	Nelfinavir sulfone
SI-4491	(S)-2-(2-Chloro-5H-chromeno[2,3-b]pyridin-5-yl)-2-methylpropanoic acid
SI-186	3-(5-Methyl-1H-imidazol-2-yl)pyridine
SI-1713	Ethyl 5-(2-chloropyridin-4-yl)-4-methyl-4H-1,2,4-triazole-3-carboxylate
SA-095	4-[2-(4-Nitrophenoxy)ethyl]morpholine
SI-4614	1-Amino-1H-pyrrole-2-carboxamide
SL-5066	Telmisartan EP impurity E
SL-5521	Cinacalcet USP related compound B
SI-4257	(S)-2-(3-(tert-Butyl)ureido)-3,3-dimethylbutanoic acid

SL-2585

Desmethyl bosentan, 98% (HPLC)

Recently Viewed Products

Related Products