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SL-2596

Bosentan USP related compound A, 98%

CAS No. : 
[150727-06-3]    
MDL No. : 
MFCD09751194
Synonyms : 4-(tert-Butyl)-N-(6-chloro-5-(2-methoxyphenoxy)-[2,2'-bipyrimidin]-4-yl)benzenesulfonamide

Price and Availability
Pack Size Price in USD Quantity Availability Shipping Status
10MG100.00 In Stock Estimated to Ship on 01.06.2025
25MG250.00 In Stock Estimated to Ship on 01.06.2025
50MG450.00 In Stock Estimated to Ship on 01.06.2025
100MG800.00 In Stock Estimated to Ship on 01.06.2025
Chemical Properties
C25H24ClN5O4S 526.01
Pale yellow solid Not available
For Laboratory research use only, not for drug, household or other uses.
Applications : This is an intermediate in the preparation of Bosentan, which is a competitive and dual antagonist of endothelin-1 (ET) for the ETA and ETB receptors with Ki of 4.7 nM and 95 nM in human SMC, respectively.
References : Dhillon S. et al.: Am J. Cardiovasc Drugs 9 (5), 331-350, 2009; Akamata K. et al. Arthritis Res Ther. 16 (2), R86, 2014; Iglarz M. et al. Life Sci. 118 (2), 333-339, 2014; Son G. Y. et al. PLoS One 11(12), e0167713, 2016.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SL-2596

Product Name : Bosentan USP related compound A

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