SynInnova Laboratories Inc.

SL-2586

Desmethyl bosentan-d₄, 98% (HPLC)

Isotopic Purity :

98 atom % D

Synonyms : 4-(tert-Butyl)-N-(6-(2-hydroxyethoxy-d₄)-5-(2-hydroxyphenoxy)-[2,2'-bipyrimidin]-4-yl)benzenesulfonamide; Bosentan O-desmethyl-d₄ impurity; Ro 47-8634-d₄

Price and Availability
Pack Size	Price in USD	Quantity	Availability	Shipping Status
5MG	680.00	- +	Back Order	Estimated to Ship on 12.03.2024
10MG	1280.00	- +	Back Order	Estimated to Ship on 12.03.2024

Chemical Properties
Mol. Formula : C₂₆H₂₃D₄N₅O₆S	Mol. Weight : 541.61
Appearance : Yellow solid	Melting Point : Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Desmethyl bosentan-d4 is a deuterium labelled metabolite of Bosentan, which is a competitive and dual antagonist of endothelin-1 (ET) for the ET_A and ET_B receptors with Ki of 4.7 nM and 95 nM in human SMC, respectively.

References : Dhillon S. et al.: Am J. Cardiovasc Drugs 9 (5), 331-350, 2009; Akamata K. et al. Arthritis Res Ther. 16 (2), R86, 2014; Iglarz M. et al. Life Sci. 118 (2), 333-339, 2014; Son G. Y. et al. PLoS One 11(12), e0167713, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

To receive price and delivery information on larger quantities, please complete the form below and we will respond promptly.

If you login prior to completion of the form, your contact information will automatically populate.

Your request for quote will also be accepted by e-mail at sales@syninnova.com or Fax: +1 780 485 2963.

Product ID : SL-2586

Product Name : Desmethyl bosentan-d₄

Note : If you do not find your required compound in our catalogue, or not commercially available, please contact us, we will assist you to get your desired molecule. We only charge if we deliver to your satisfaction.

Site is under construction and it will coming soon. Please contact us at sales@syninnova.com for COA. Thank you!

Site is under construction and it will coming soon. Please contact us at sales@syninnova.com for HNMR. Thank you!

Related Products

SL-2590	Hydroxy bosentan-d₆
SL-2593	Bosentan USP related compound C
SL-2584	Bosentan-13C2, d4
SL-2812	Bosentan diacid impurity
SL-2586	Desmethyl bosentan-d₄
SL-2583	Bosentan-d₄
SL-2581	Bosentan
SL-2814	2-(tert-Butyl)benzenesulfonamide
SL-2592	Hydroxy desmethyl bosentan-d₄
SL-2594	Bosentan-d₄ USP related compound C
SL-2595	Bosentan impurity
SL-2813	Bosentan monoacid impurity

SL-2586	Desmethyl bosentan-d₄
SI-3256	3-Bromophenyl 2-(2,5-dibromophenyl)acetate
SI-345	Diethyl (2-aminoethyl)phosphonate
SL-3205	Tetrahydro erlotinib
SA-750	2,2-Dimethyl-3-pentanol
SI-385	2-Bromo-3,6-dimethoxybenzyl alcohol
SL-4537	Enalaprilat
SI-176	N-Boc-2- tert-butyldimethylsiloxypyrrole
SI-016	4-Chloro-6-(4-methoxyphenoxy)pyrimidine
SL-4539	Enalapril EP impurity D
SI-4773	N-((4-Chloro-1-(tetrahydro-2H-pyran-2-yl)-1H-benzo[d]imidazol-5-yl)methyl)ethanamine
SL-995	rac-Epinephrine-d₃

SL-2586

Desmethyl bosentan-d4, 98% (HPLC)

Recently Viewed Products

Related Products

Desmethyl bosentan-d₄, 98% (HPLC)