SynInnova Laboratories Inc.

SL-3738

Pemetrexed dimer (R) diasteromer, 98%

CAS No. :

[1802552-04-0]

Synonyms : (2S,2'S)-2,2'-((4,4'-(((R)-2,2'-Diamino-4,4',6-trioxo-4,4',5,6,7,7'-hexahydro-1H,3'H-[5,6'-bipyrrolo[2,3-d]pyrimidine]-5,5'-diyl)bis(ethane-2,1-diyl))bis(benzoyl))bis(azanediyl))dipentanedioic acid: Pemetrexed EP impurity B

Price and Availability
Pack Size	Price in USD	Quantity	Availability	Shipping Status
5MG	1280.00	- +	In Stock	Estimated to Ship on 12.06.2024
10MG	2280.00	- +	In Stock	Estimated to Ship on 12.06.2024

Chemical Properties
Mol. Formula : C₄₀H₄₀N₁₀O₁₃	Mol. Weight : 868.80
Appearance : Off-white solid	Melting Point : Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : It is an impurity of Pemetrexed (Pemetrexed EP impurity B), which is a novel antifolate and antimetabolite for dihydrofolate reductase-thymidylate synthase (DHFR-TS). It is used to treat for pleural mesothelioma (cancer of the outer covering of the lungs) non small cell lung cancer (NSCLC).

References : Shih C. et al.: Cancer Res., 57(6), 1116-1123, 1997; Iwahori K. et al.: Int J. Cancer., 132(2), 459-471, 2013; Teicher B. A. et al.: Clin. Cancer Res. , 6(3), 1016-1023, 2000.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SL-3738

Product Name : Pemetrexed dimer (R) diasteromer

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