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SL-3738 

Pemetrexed dimer (R) diasteromer, 98%

CAS No. : 
[1802552-04-0]    
Synonyms : (2S,2'S)-2,2'-((4,4'-(((R)-2,2'-Diamino-4,4',6-trioxo-4,4',5,6,7,7'-hexahydro-1H,3'H-[5,6'-bipyrrolo[2,3-d]pyrimidine]-5,5'-diyl)bis(ethane-2,1-diyl))bis(benzoyl))bis(azanediyl))dipentanedioic acid: Pemetrexed EP impurity B

Price and Availability
Pack Size Price in USD Quantity Availability Shipping Status
5MG1280.00 In Stock Estimated to Ship on 01.06.2025
10MG2280.00 In Stock Estimated to Ship on 01.06.2025
Chemical Properties
C40H40N10O13 868.80
Off-white solid Not available
For Laboratory research use only, not for drug, household or other uses.
Applications : It is an impurity of Pemetrexed (Pemetrexed EP impurity B), which is a novel antifolate and antimetabolite for dihydrofolate reductase-thymidylate synthase (DHFR-TS). It is used to treat for pleural mesothelioma (cancer of the outer covering of the lungs) non small cell lung cancer (NSCLC).
References : Shih C. et al.: Cancer Res., 57(6), 1116-1123, 1997; Iwahori K. et al.: Int J. Cancer., 132(2), 459-471, 2013; Teicher B. A. et al.: Clin. Cancer Res. , 6(3), 1016-1023, 2000.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SL-3738

Product Name : Pemetrexed dimer (R) diasteromer

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