SynInnova Laboratories Inc.

SL-3746

Pemetrexed-1-methyl ester, 98%

CAS No. :

[1265908-63-1]

Synonyms : (S)-4-(4-(2-(2-Amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzamido)-5-methoxy-5-oxopentanoic acid; Pemetrexed impurity 3

Price and Availability
Pack Size	Price in USD	Quantity	Availability	Shipping Status
10MG	120.00	- +	Back Order	Estimated to Ship on 01.20.2025
50MG	580.00	- +	Back Order	Estimated to Ship on 01.20.2025
100MG	980.00	- +	Back Order	Estimated to Ship on 01.20.2025

Chemical Properties
Mol. Formula : C₂₁H₂₃N₅O₆	Mol. Weight : 441.44
Appearance : Solid	Melting Point : Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Pemetrexed-1-methyl ester is an impurity of Pemetrexed, which is a novel antifolate and antimetabolite for dihydrofolate reductase-thymidylate synthase (DHFR-TS). It is used to treat for pleural mesothelioma (cancer of the outer covering of the lungs) non small cell lung cancer (NSCLC).

References : Shih C. et al.: Cancer Res., 57(6), 1116-1123, 1997; Iwahori K. et al.: Int J. Cancer., 132(2), 459-471, 2013; Teicher B. A. et al.: Clin. Cancer Res. , 6(3), 1016-1023, 2000.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SL-3746

Product Name : Pemetrexed-1-methyl ester

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SL-3749	Pemetrexed impurity 19
SL-3742	Pemetrexed (R) enantiomer
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SL-3744	N-Methyl pemetrexed L-glutamic acid
SL-3737	N-Methyl pemetrexed-d₃
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