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SL-3746

Pemetrexed-1-methyl ester, 98%

CAS No. : 
[1265908-63-1]    
Synonyms : (S)-4-(4-(2-(2-Amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzamido)-5-methoxy-5-oxopentanoic acid; Pemetrexed impurity 3

Price and Availability
Pack Size Price in USD Quantity Availability Shipping Status
10MG120.00 Back Order Estimated to Ship on 12.20.2024
50MG580.00 Back Order Estimated to Ship on 12.20.2024
100MG980.00 Back Order Estimated to Ship on 12.20.2024
Chemical Properties
C21H23N5O6 441.44
Solid Not available
For Laboratory research use only, not for drug, household or other uses.
Applications : Pemetrexed-1-methyl ester is an impurity of Pemetrexed, which is a novel antifolate and antimetabolite for dihydrofolate reductase-thymidylate synthase (DHFR-TS). It is used to treat for pleural mesothelioma (cancer of the outer covering of the lungs) non small cell lung cancer (NSCLC).
References : Shih C. et al.: Cancer Res., 57(6), 1116-1123, 1997; Iwahori K. et al.: Int J. Cancer., 132(2), 459-471, 2013; Teicher B. A. et al.: Clin. Cancer Res. , 6(3), 1016-1023, 2000.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SL-3746

Product Name : Pemetrexed-1-methyl ester

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