SynInnova Laboratories Inc.

SL-3748

LY-368962, 98%

CAS No. :

[193281-05-9]

Synonyms : N-[4-[3-(2,6-Diamino-1,4-dihydro-4-oxo-5-pyrimidinyl)-3-oxopropyl]benzoyl]-L-glutamic acid; Pemetrexed impurity 13

Price and Availability
Pack Size	Price in USD	Quantity	Availability	Shipping Status
10MG	120.00	- +	Back Order	Estimated to Ship on 01.20.2025
100MG	980.00	- +	Back Order	Estimated to Ship on 01.20.2025

Chemical Properties
Mol. Formula : C₁₉H₂₁N₅O₇	Mol. Weight : 431.40
Appearance : Off-white solid	Melting Point : Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : LY-368962 is a metabolite of Pemetrexed, which is a novel antifolate and antimetabolite for dihydrofolate reductase-thymidylate synthase (DHFR-TS). It is used to treat for pleural mesothelioma (cancer of the outer covering of the lungs) non small cell lung cancer (NSCLC).

References : Shih C. et al.: Cancer Res., 57(6), 1116-1123, 1997; Iwahori K. et al.: Int J. Cancer., 132(2), 459-471, 2013; Teicher B. A. et al.: Clin. Cancer Res. , 6(3), 1016-1023, 2000; Woodland J. M. et al.: Drug Metab. Dispos., 25, 693, 1997.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SL-3748

Product Name : LY-368962

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SL-3737	N-Methyl pemetrexed-d₃
SL-3736	N-Methyl pemetrexed
SL-3749	Pemetrexed impurity 19
SL-3752	Pemetrexed L-glutamic acid ethyl ester
SL-3756	4-(2-(2-Amino-4,6-dioxo-4,5,6,7-tetrahydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzoic acid
SL-3753	Pemetrexed diethylester N,N-dimethylformamidine
SL-3750	Pemetrexed alpha-hydroxy lactum
SL-3744	N-Methyl pemetrexed L-glutamic acid
SL-3745	Pemetrexed-5-methyl ester
SL-3747	Pemetrexed methyl ester

SL-3748	LY-368962
SI-923	Ethyl 1-(2,6-difluorobenzyl)-4-(2-oxoethyl)-1H-pyrazole-3-carboxylate
SL-3258	Fluconazole
SL-3274	Fluconazole impurity 9
SL-3006	Dasatinib-d₄ N-oxide
SL-3022	Des-6-[4-(2-hydroxyethyl)-1-piperazinyl]-6-chloro-O-pivalate dasatinib
SL-3271	Fluconazole impurity 5
SL-3014	3-Chloro dasatinib
SL-3006	Dasatinib-d₄ N-oxide
SL-3014	3-Chloro dasatinib
SL-3022	Des-6-[4-(2-hydroxyethyl)-1-piperazinyl]-6-chloro-O-pivalate dasatinib
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SL-3748

LY-368962, 98%

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