SynInnova Laboratories Inc.

SL-3748

LY-368962, 98%

CAS No. :

[193281-05-9]

Synonyms : N-[4-[3-(2,6-Diamino-1,4-dihydro-4-oxo-5-pyrimidinyl)-3-oxopropyl]benzoyl]-L-glutamic acid; Pemetrexed impurity 13

Price and Availability
Pack Size	Price in USD	Quantity	Availability	Shipping Status
10MG	120.00	- +	Back Order	Estimated to Ship on 12.20.2024
100MG	980.00	- +	Back Order	Estimated to Ship on 12.20.2024

Chemical Properties
Mol. Formula : C₁₉H₂₁N₅O₇	Mol. Weight : 431.40
Appearance : Off-white solid	Melting Point : Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : LY-368962 is a metabolite of Pemetrexed, which is a novel antifolate and antimetabolite for dihydrofolate reductase-thymidylate synthase (DHFR-TS). It is used to treat for pleural mesothelioma (cancer of the outer covering of the lungs) non small cell lung cancer (NSCLC).

References : Shih C. et al.: Cancer Res., 57(6), 1116-1123, 1997; Iwahori K. et al.: Int J. Cancer., 132(2), 459-471, 2013; Teicher B. A. et al.: Clin. Cancer Res. , 6(3), 1016-1023, 2000; Woodland J. M. et al.: Drug Metab. Dispos., 25, 693, 1997.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SL-3748

Product Name : LY-368962

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Site is under construction and it will coming soon. Please contact us at sales@syninnova.com for COA. Thank you!

Site is under construction and it will coming soon. Please contact us at sales@syninnova.com for HNMR. Thank you!

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SL-3753	Pemetrexed diethylester N,N-dimethylformamidine
SL-3748	LY-368962
SL-3747	Pemetrexed methyl ester
SL-3742	Pemetrexed (R) enantiomer
SL-3735	Pemetrexed-d₅
SL-3750	Pemetrexed alpha-hydroxy lactum
SL-3752	Pemetrexed L-glutamic acid ethyl ester
SL-3756	4-(2-(2-Amino-4,6-dioxo-4,5,6,7-tetrahydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzoic acid
SL-3754	Pemetrexed N,N-dimethylformamidine
SL-3745	Pemetrexed-5-methyl ester
SL-3744	N-Methyl pemetrexed L-glutamic acid

SL-3748	LY-368962
SI-1917	1-(3-Bromo-1-(tetrahydro-2H-pyran-4-yl)-6,7-dihydro-1H-pyrazolo[4,3-c]pyridin-5(4H)-yl)ethanone
SL-526	7-Methoxycoumarin-4-acetic acid
SL-513	tert-Butyl 2-{[(7-hydroxy-2-oxo-2H-chromen-4-yl)acetyl]amino}ethylcarbamate
SI-2264	(S)-5-Bromo-4-chloro-1-(3-methylbutan-2-yl)-2-oxo-1,2-dihydropyridine-3-carbonitrile
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SL-512	7-Hydroxycoumarin-4-acetic acid succinimidyl ester
SL-3734	Pemetrexed
SL-1056	Anastrozole-¹³C₄
SA-1282	6-Chloro-1H-pyrazolo[3,4-d]pyrimidine
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SL-3748

LY-368962, 98%

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