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SL-3743

LY-338979, 98%

CAS No. : 
[193281-00-4]    
Synonyms : (2S)-2-(4-(2-(2-Amino-4,6-dioxo-4,5,6,7-tetrahydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzamido)pentanedioic acid; Pemetrexed keto impurity

Price and Availability
Pack Size Price in USD Quantity Availability Shipping Status
5MG400.00 Back Order Estimated to Ship on 01.20.2025
25MG1600.00 Back Order Estimated to Ship on 01.20.2025
Chemical Properties
C20H21N5O7 443.41
Light orange solid Not available
For Laboratory research use only, not for drug, household or other uses.
Applications : LY-338979 is a metabolite of Pemetrexed, which is a novel antifolate and antimetabolite for dihydrofolate reductase-thymidylate synthase (DHFR-TS). It is used to treat for pleural mesothelioma (cancer of the outer covering of the lungs) non small cell lung cancer (NSCLC).
References : Shih C. et al.: Cancer Res., 57(6), 1116-1123, 1997; Iwahori K. et al.: Int J. Cancer., 132(2), 459-471, 2013; Teicher B. A. et al.: Clin. Cancer Res. , 6(3), 1016-1023, 2000; Woodland J. M. et al.: Drug Metab. Dispos., 25, 693, 1997.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SL-3743

Product Name : LY-338979

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