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SL-6251

Proguanil EP impurity G HCl, >98%

CAS No. : 
[1071546-52-5]    
Synonyms : N1-(3-Chlorophenyl)-N3-(propan-2-yl)imidodicarbonimidic diamide hydrochloride; Proguanil USP related compound G HCl

Price and Availability
Pack Size Price in USD Quantity Availability Shipping Status
50MG150.00 Back Order Estimated to Ship on 01.19.2025
500MG1180.00 Back Order Estimated to Ship on 01.19.2025
Chemical Properties
C11H16ClN5 . HCl 290.19
White to Off-white solid Not available
For Laboratory research use only, not for drug, household or other uses.
Applications : This is an impurity of Proguanil (Proguanil EP impurity G HCl), which is a prophylactic antimalarial drug. It inhibits the dihydrofolate reductase of plasmodia and thereby blocks the biosynthesis of purines and pyrimidines, which are essential for DNA synthesis and cell multiplication.
References : Srivastava I. K. et al.: Antimicrob Agents Chemother., 43(6), 1334-9, 1999;
Lochner M. et al.: J. Pharmacol Exp Ther., 351(3), 674-84, 2004; Stephen A. O. et al.: J. Toxicol Sci., 36(5), 587-99, 2011; Iguchi A. et al.: Vet. Parasitol. 197(3-4), 527-33, 2013.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SL-6251

Product Name : Proguanil EP impurity G HCl

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