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SL-6251

Proguanil EP impurity G HCl, >98%

CAS No. : 
[1071546-52-5]    
Synonyms : N1-(3-Chlorophenyl)-N3-(propan-2-yl)imidodicarbonimidic diamide hydrochloride; Proguanil USP related compound G HCl

Price and Availability
Pack Size Price in USD Quantity Availability Shipping Status
50MG150.00
-
+
Back Order Estimated to Ship on 12.18.2024
500MG1180.00
-
+
Back Order Estimated to Ship on 12.18.2024
Chemical Properties
C11H16ClN5 . HCl 290.19
White to Off-white solid Not available
For Laboratory research use only, not for drug, household or other uses.
Applications : This is an impurity of Proguanil (Proguanil EP impurity G HCl), which is a prophylactic antimalarial drug. It inhibits the dihydrofolate reductase of plasmodia and thereby blocks the biosynthesis of purines and pyrimidines, which are essential for DNA synthesis and cell multiplication.
References : Srivastava I. K. et al.: Antimicrob Agents Chemother., 43(6), 1334-9, 1999;
Lochner M. et al.: J. Pharmacol Exp Ther., 351(3), 674-84, 2004; Stephen A. O. et al.: J. Toxicol Sci., 36(5), 587-99, 2011; Iguchi A. et al.: Vet. Parasitol. 197(3-4), 527-33, 2013.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SL-6251

Product Name : Proguanil EP impurity G HCl

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