SynInnova Laboratories Inc.

SL-6236

Proguanil-d₄, >98% (HPLC)

Isotopic Purity :

98 atom % D

CAS No. :

[1189805-15-9]

Synonyms : N1-(4-Chlorophenyl-d₄)-N3-(propan-2-yl)imidodicarbonimidic diamide ; Chloroguanide-d₄; Chlorguanide-d₄

Price and Availability
Pack Size	Price in USD	Quantity	Availability	Shipping Status
5MG	680.00	- +	Back Order	Estimated to Ship on 12.18.2024
10MG	1180.00	- +	Back Order	Estimated to Ship on 12.18.2024

Chemical Properties
Mol. Formula : C₁₁H₁₂D₄ClN₅	Mol. Weight : 257.76
Appearance : White to Off-white solid	Melting Point : Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Proguanil-d4 is a deuterium labelled version of Proguanil, which is a prophylactic antimalarial drug. It inhibits the dihydrofolate reductase of plasmodia and thereby blocks the biosynthesis of purines and pyrimidines, which are essential for DNA synthesis and cell multiplication.

References : Srivastava I. K. et al.: Antimicrob Agents Chemother., 43(6), 1334-9, 1999;
Lochner M. et al.: J. Pharmacol Exp Ther., 351(3), 674-84, 2004; Stephen A. O. et al.: J. Toxicol Sci., 36(5), 587-99, 2011; Iguchi A. et al.: Vet. Parasitol. 197(3-4), 527-33, 2013.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SL-6236

Product Name : Proguanil-d₄

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SL-6236

Proguanil-d4, >98% (HPLC)

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