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SL-6248

Proguanil EP impurity E, >98%

CAS No. : 
[1482-62-8]    
MDL No. : 
MFCD01724336
Synonyms : N-(4-Chlorophenyl)-N'-cyanoguanidine; P-Chlorophenyl-cyanoguanidine; Proguanil USP related compound E

Price and Availability
Pack Size Price in USD Quantity Availability Shipping Status
1G580.00
-
+
Back Order Estimated to Ship on 01.19.2025
5G1880.00
-
+
Back Order Estimated to Ship on 01.19.2025
Chemical Properties
C8H7ClN4 194.62
White to Off-white solid Not available
For Laboratory research use only, not for drug, household or other uses.
Applications : This is an impurity of Proguanil (Proguanil EP impurity E), which is a prophylactic antimalarial drug. It inhibits the dihydrofolate reductase of plasmodia and thereby blocks the biosynthesis of purines and pyrimidines, which are essential for DNA synthesis and cell multiplication.
References : Srivastava I. K. et al.: Antimicrob Agents Chemother., 43(6), 1334-9, 1999;
Lochner M. et al.: J. Pharmacol Exp Ther., 351(3), 674-84, 2004; Stephen A. O. et al.: J. Toxicol Sci., 36(5), 587-99, 2011; Iguchi A. et al.: Vet. Parasitol. 197(3-4), 527-33, 2013.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SL-6248

Product Name : Proguanil EP impurity E

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