SynInnova Laboratories Inc.

SL-6248

Proguanil EP impurity E, >98%

CAS No. :

[1482-62-8]

MDL No. :

MFCD01724336

Synonyms : N-(4-Chlorophenyl)-N'-cyanoguanidine; P-Chlorophenyl-cyanoguanidine; Proguanil USP related compound E

Price and Availability
Pack Size	Price in USD	Quantity	Availability	Shipping Status
1G	580.00	- +	Back Order	Estimated to Ship on 12.18.2024
5G	1880.00	- +	Back Order	Estimated to Ship on 12.18.2024

Chemical Properties
Mol. Formula : C₈H₇ClN₄	Mol. Weight : 194.62
Appearance : White to Off-white solid	Melting Point : Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Proguanil (Proguanil EP impurity E), which is a prophylactic antimalarial drug. It inhibits the dihydrofolate reductase of plasmodia and thereby blocks the biosynthesis of purines and pyrimidines, which are essential for DNA synthesis and cell multiplication.

References : Srivastava I. K. et al.: Antimicrob Agents Chemother., 43(6), 1334-9, 1999;
Lochner M. et al.: J. Pharmacol Exp Ther., 351(3), 674-84, 2004; Stephen A. O. et al.: J. Toxicol Sci., 36(5), 587-99, 2011; Iguchi A. et al.: Vet. Parasitol. 197(3-4), 527-33, 2013.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SL-6248

Product Name : Proguanil EP impurity E

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