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SL-6242

Proguanil-d7 hydrochloride, >98% (HPLC)

Isotopic Purity : 
99 atom % D
Synonyms : N1-(4-Chlorophenyl)-N3-(propan-2-yl-d7)imidodicarbonimidic diamide hydrochloride; Chloroguanide-d7 hydrochloride; Chlorguanide-d7 hydrochloride

Price and Availability
Pack Size Price in USD Quantity Availability Shipping Status
5MG680.00 Back Order Estimated to Ship on 12.18.2024
10MG1280.00 Back Order Estimated to Ship on 12.18.2024
Chemical Properties
C11H9D7ClN5 . HCl 297.23
White to Off-white solid Not available
For Laboratory research use only, not for drug, household or other uses.
Applications : Proguanil-d7 HCl is a deuterium labelled version of Proguanil, which is a prophylactic antimalarial drug. It inhibits the dihydrofolate reductase of plasmodia and thereby blocks the biosynthesis of purines and pyrimidines, which are essential for DNA synthesis and cell multiplication.
References : Srivastava I. K. et al.: Antimicrob Agents Chemother., 43(6), 1334-9, 1999;
Lochner M. et al.: J. Pharmacol Exp Ther., 351(3), 674-84, 2004; Stephen A. O. et al.: J. Toxicol Sci., 36(5), 587-99, 2011; Iguchi A. et al.: Vet. Parasitol. 197(3-4), 527-33, 2013.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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Product ID : SL-6242

Product Name : Proguanil-d7 hydrochloride

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